Regorafenib (BAY 73-4506, Fluoro-Sorafenib, Resihance, Stivarga) is a multi-target inhibitor for¿VEGFR1,¿VEGFR2,¿VEGFR3,¿PDGFR?,¿Kit (c-Kit),¿RET (c-RET)¿and¿Raf-1¿with¿IC50¿of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces¿autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.